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The BIOFIRE System and Your Immune System The BIOFIRE System offers syndromic testing for infectious diseases allowing healthcare providers to select the appropriate test first time Patients benefit from faster diagnosis and more targeted therapy Clinicians benefit from improved stewardship of antibiotics Labs save money and increase efficiency The BioFire Pneumonia Plus Panel PN panel tests native sputum including miniBAL and endotracheal lavage and bronchoalveolar liquids including mini BAL for 33 clinically significant pathogens and resistance genes to antimicrobials within an hour Respiratory The burning of biomass wood plants and other organic material creates gaseous pollutants and fine particulate matter which negatively impact the respiratory system Moreover the environmental problems caused by forest fires such as droughts can be potentiated by climate change thereby increasing their negative impacts on the health of humans In the United States wildfire smoke has been linked to hospitalizations for respiratory diseases such as asthma COPD and lung cancer This kind of pollution to the air also increases the risk of developing cardiovascular disease and is a major cause of the burden of disease among the most vulnerable populations During the COVID19 pandemic many communities were exposed to harmful levels of air pollution resulting from wildfires However the public health response to this environmental problem is sporadic and mainly focused on educating people about symptom management This gap in knowledge is alarming considering the evidence of potential health risks resulting from the continual exposure to smoke and other sources of poor air quality Researchers are now looking at the best way to safeguard publics health during future incidents of this type NIH is funding research on this crucial public health issue through the BLUE CORAL study as well as its successor FIRE CORAL For the first time a prospective cohort study will examine longterm effects resulting from exposure to smoke from wildfires as well as other sources FIRE CORAL is looking for adult participants hospitalized for the index episode of COVID19 who are fluent in English or Spanish and are not pregnant ethanol biofuel fireplace for FIRE CORAL includes a battery of tests inperson that objectively measure lung function tests and pulmonary imaging as well as functional assessments The lungs are especially sensitive to the effects of smoke and other particles due to the fact that they can trigger or worsen chronic respiratory illnesses such as emphysema asthma and COPD and increase the risk of contracting pneumonia A number of steps can be taken to stop or minimize the negative health effects resulting from exposures to smoke such as avoiding outdoor activities when possible and wearing the EPAs N95 mask which is designed to trap fine particles Smoke can also cause irritation of the throat and eyes and can cause an irritated nose To reduce the symptoms drink plenty of water and take medicines that help reduce inflammation like corticosteroids Bloodstream Your bloodstream is at the forefront of fighting off germs that enter your body Dendritic cells specific cells serve as the call center for your fire department They collect antigens from germs and release proteins that signal other white cells to fight them The total number of white blood cells differentials and band cells grew after firefighters firefighting activities as compared to levels following strenuous exercise without firefighting Skin As the wildfires in California produced smoke and ash into the air over the course of winter and fall dermatologists were concerned about how this could affect the skin of people exposed to it Maria Wei a graduate student at University of California Irvine is researching how extreme wildfire pollution affects the skin Her research was published in Scientific Reports on April 22 Weis study shows that the temperature changes of the skin dependent on the amount of time the body has been exposed It could take up to two hours for the skin of someone to reach their flash pointthe moment at which it begins to burn and then turn ashy It is important to avoid staying near a fire pit or campfire and wear protective clothing if going outside on a hot or humid day While it is important to be vigilant against wildfirerelated pollution theres no way to stop forest fires from occurring Wei is forecasting that the number of people suffering the effects of wildfires will rise as climate change causes more and more forests to burn This means that more people will need to wear hats and long sleeves and also thick moisturizers Air pollution from wildfires can exacerbate atopic skin dermatitis which causes itchy skin for many people The particles in smoke can clog up pores which can cause skin irritation Another issue is the fact that atopic dermatitis can make people more sensitive to UV light which can be aggravated by smoke from wildfires This could lead to people seeking out tanning salons and get tanned with less protection A treatment with ice and fire could help to reduce atopic dermatitis symptoms however it is not recommended for anyone with an open wound or rash People who suffer from acne are advised to be cautious and if youre nursing or pregnant its best to steer clear of this treatment completely The IS Clinical Fire Ice Facial located at Novuskin Las Vegas premier membership MedSpa is a resultsdriven intensive facial that bridges between an easy facelift and a peel without requiring time off Its designed to smooth the skin improve the appearance of rosacea lessen acne scarring reduce fine lines and encourage cellular renewal This is a great treatment to provide your skin with a radiant glow Infections The human body is made up of a complex set of organs and tissue which work together to defend us from infection Infections are caused by microscopic organisms like bacteria viruses parasites and fungi that infect healthy cells and cause them to replicate out of control When this happens your immune system may react with symptoms of illness The symptoms could range from a runny nose to an upset stomach as well as an increase in fever swelling of lymph glands or an itchy rash The symptoms you experience can be affected by the nature of the infection its location and even your temperature Infections can be spread through a variety of methods but the most common are spread from person to by droppings that hang in the air after coughing or sneezing Bacterial infections like strep throat tuberculosis meningococcal disease and Legionnaires disease spread in this manner as do some viral infections such as the common cold and influenza Some bacterial infections such as skin infections or sexually transmitted diseases STIs like Chlamydia and gonorrhea can be transmitted through direct contact with affected mucous or tissue surfaces or indirectly through contaminated surfaces Certain bacterial infections are transmitted by insects like ticks fleas or mosquitoes The parasites viruses and other microorganisms are small enough to enter your bloodstream and infect your cells This can lead to serious diseases like the common cold or AIDS Fungi can cause skin conditions like ringworm and athletes feet and others can infect the lungs and nervous system The BioFire PN Panel uses our innovative FilmArray technology to detect an extensive list of pathogens responsible for upper respiratory infections in sputum and bronchoalveolar lavage fluid samples The kit comes with an reagent pouch that houses all the necessary chemistry to perform reverse transcription PCR nested multiplex testing and detection with a single device This is a simple solution that assists clinicians identify and treat patients with various respiratory symptoms This test has been given an Emergency Use Authorization It is available in bioMerieux CLIA medium and high complexity labs